Publications 2017-2021
104. Targeted optical fluorescence imaging: a meta-narrative review and future perspectives
EJNMMI 2021, 48, 4272–4292
H. M. Schouw, L. A. Huisman, Y. F. Janssen, R. H. J. A. Slart, R. J. H. Borra, A. T. M. Willemsen, A. H. Brouwers, J. M. van Dijl, R. A. Dierckx, G. M. van Dam, W. Szymanski, H. H. Boersma, S. Kruijff*
103. Phenylimino Indolinone: a Green Light Responsive T-Type Photoswitch Exhibiting Negative Photochromism
Angew. Chem. Int. Ed. 2021, 60, 25290-25295
Stefano Crespi,* Nadja A. Simeth, Mariangela Di Donato, Sandra Doria, Charlotte N. Stindt, Michiel F. Hilbers, Ferdinand L. Kiss, Ryojun Toyoda, Sammo Wesseling, Wybren Jan Buma, Ben L. Feringa,* Wiktor Szymanski*
102. Molecular photoswitches in aqueous environments
Chem. Soc. Rev. 2021, 50, 12377 - 12449
Jana Volaric, Wiktor Szymanski, Nadja A. Simeth,* Ben L. Feringa*
101. Let’s embrace optical imaging: a growing branch on the clinical molecular imaging tree (Editorial)
EJNMMI 2021, 48, 4120–4128
Milou E. Noltes, Gooitzen M. van Dam, Wouter B. Nagengast, Pieter J. van der Zaag, Riemer H. J. A. Slart, Wiktor Szymanski, Schelto Kruijff, Rudi A. J. O. Dierckx*
100. Ultrafast Photoclick Reaction for Selective 18F-Positron Emission Tomography Tracer Synthesis in Flow
J. Am. Chem. Soc. 2021, 143, 10041-10047
Youxin Fu, Hugo Helbert, Nadja A. Simeth, Stefano Crespi, Gerbren B. Spoelstra, Jan Maarten van Dijl, Marleen van Oosten, Luiza Reali Nazario, Dion van der Born, Gert Luurtsema, Wiktor Szymanski,* Philip H. Elsinga,* Ben L. Feringa*
99. Rational Design of a Photoswitchable DNA Glue Enabling High Regulatory Function and Supramolecular Chirality Transfer
Chem. Sci. 2021, 12, 9207-9220
Nadja A. Simeth, Shotaro Kobayashi, Piermichele Kobauri, Stefano Crespi, Wiktor Szymanski, Kazuhiko Nakatani,* Chikara Dohno,* and Ben L. Feringa*
98. Reversible Modulation of Circadian Time with Chronophotopharmacology
Nat. Comm. 2021, 12, 3164
Dušan Kolarski, Carla Miró Vinyals, Akiko Sugiyama, Ashutosh Srivastava, Daisuke Ono, Yoshiko Nagai, Mui Iida, Kenichiro Itami, Florence Tama, Wiktor Szymanski,* Tsuyoshi Hirota,* Ben L. Feringa*
97. Mechanism of Resistance Development in E. coli against TCAT, a Trimethoprim-Based Photoswitchable Antibiotic
Pharmaceuticals 2021, 14, 392
Anna I. Lauxen, Piermichele Kobauri, Michael Wegener, Mickel J. Hansen, Nicole S. Galenkamp, Giovanni Maglia, Wiktor Szymanski,* Ben L. Feringa* and Oscar P. Kuipers*
96. Biaryl sulfonamides as cisoid azosteres for photopharmacology
Chem. Comm. 2021, 57, 4126-4129
Piermichele Kobauri, Wiktor Szymanski,* Fangyuan Cao, Sebastian Thallmair, Siewert J. Marrink, Martin D. Witte, Frank J. Dekker* and Ben L. Feringa*
95. Reductive stability evaluation of 6-azopurine photoswitches for the regulation of CKIa activity and circadian rhythm
Org. Biomol. Chem. 2021, 19, 2312 - 2321
Dušan Kolarski, Akiko Sugiyama, Theo Rodat, Albert Schulte, Christian Peifer, Kenichiro Itami, Tsuyoshi Hirota,* Ben L. Feringa,* and Wiktor Szymanski*
94. Tailoring the optical and dynamic properties of iminothioindoxyl photoswitches through acidochromism
Chem. Sci. 2021, 12, 4588-4598
Miroslav Medved,* Mark W. H. Hoorens, Mariangela Di Donato, Adčle D. Laurent, Jiayun Fan, Maria Taddei, Michiel Hilbers, Ben L. Feringa, Wybren Jan Buma, Wiktor Szymanski*
93. Photopharmacological Manipulation of Mammalian CRY1 for Regulation of the Circadian Clock
J. Am. Chem. Soc. 2021, 143, 2078–2087
Dušan Kolarski, Simon Miller, Tsuyoshi Oshima, Yoshiko Nagai, Yugo Aoki, Piermichele Kobauri, Ashutosh Srivastava, Akiko Sugiyama, Kazuma Amaike, Ayato Sato, Florence Tama, Wiktor Szymanski, Ben L. Feringa,* Kenichiro Itami,* and Tsuyoshi Hirota*
92. Structural Aspects of Photopharmacology: Insight into the Binding of Photoswitchable and Photocaged Inhibitors to the Glutamate Transporter
J. Am. Chem. Soc. 2021, 143, 1513–1520
Valentina Arkhipova, Haigen Fu, Mark W. H. Hoorens, Gianluca Trinco, Lucien N. Lameijer, Egor Marin, Ben L. Feringa, Gerrit J. Poelarends, Wiktor Szymanski,* Dirk J. Slotboom,* and Albert Guskov*
91. Multivalent Probes in Molecular Imaging: Reality or Future?
Trends Mol. Med. 2021, 27, 379-393
Verena I. Boehmer, Wiktor Szymanski, Ben L. Feringa, Philip H. Elsinga*
90. Cross-coupling of [11C]methyllithium for 11C-labeled PET tracer synthesis
Chem. Comm. 2021, 57, 203-206
Hugo Helbert, Inęs Farinha Antunes, Gert Luurtsema, Wiktor Szymanski, Ben L. Feringa,* Philip H. Elsinga*
89. Photoresponsive molecular tools for emerging applications of light in medicine
Chem. Sci., 2020, 11, 11672-11691
Ilse M. Welleman, Mark W. H. Hoorens, Ben L. Feringa, Hendrikus H. Boersma, Wiktor Szymanski*
88. A photocleavable contrast agent for light-responsive MRI
Pharmaceuticals 2020, 13, 296
Friederike Reeßing, Sčvrin E. M. Huijsse, Rudi A. J. O. Dierckx, Ben L. Feringa, Ronald J.H. Borra and Wiktor Szymanski*
87.Fighting Staphylococcus aureus infections with light and photo-immunoconjugates
J. Clin. Invest. Insight 2020, 5, e13951
Mafalda Bispo, Andrea Anaya-Sanchez, Sabrina Suhani, Elisa J. M. Raineri, Marina López-Álvarez, Marjolein Heuker, Wiktor Szymanski, Francisco Romero Pastrana, Girbe Buist, Alexander R. Horswill, Kevin P. Francis, Gooitzen M. van Dam, Marleen van Oosten, Jan Maarten van Dijl*
86. A facile and reproducible synthesis of NIR-fluorescent conjugates with small targeting molecules for microbial infection imaging
ACS Omega 2020, 5, 22071-22080
Friederike Reeßing, Mafalda Bispo, Marina López-Álvarez, Marleen van Oosten, Ben L. Feringa, Jan Maarten van Dijl, Wiktor Szymanski*
85. General Principles for the Design of Visible-Light-Responsive Photoswitches: Tetra-ortho-Chloro-Azobenzenes
Angew. Chem. Int. Ed. 2020, 59, 21663-21670
Lucien N. Lameijer, Simon Budzak, Nadja A. Simeth, Mickel J. Hansen, Ben L. Feringa, Denis Jacquemin,* Wiktor Szymanski*
84. Modular medical imaging agents based on azide-alkyne Huisgen cycloadditions: Synthesis and pre-clinical evaluation of 18F-labeled PSMA-tracers for prostate cancer imaging
Chem. Eur. J. 2020, 26, 10871 –10881
Verena I. Böhmer, Wiktor Szymanski,* Keimpe-Oeds van den Berg, Chantal Mulder, Piermichele Kobauri, Hugo Helbert, Dion van den Born, Friederike Reessing, Anja Huizing,..., Gert Luurtsema, Wijnand Helfrich, Ton J. Visser, Ben L. Feringa,* Philip H. Elsinga*
83. Red – light – sensitive BODIPY photoprotecting groups for amines and their biological application in controlling heart rhythm
ChemComm 2020, 56, 5480-5483
Kaja Sitkowska, Martijn F. Hoes, Michael Lerch, Lucien Lameijer, Peter van der Meer, Wiktor Szymanski* and Ben L. Feringa*
82. A light-responsive liposomal agent for MRI contrast enhancement and monitoring of cargo delivery
ChemComm 2019, 55, 10784-10787
Friederike Reeßing, Mark C.A. Stuart, Douwe F. Samplonius, Rudi A.J.O. Dierckx, Ben L. Feringa, Wijnand Helfrich, Wiktor Szymanski*
81. Reversible Photocontrolled Nanopore Assembly
J. Am. Chem. Soc. 2019, 141, 14356-14363
Natalie L. Mutter, Jana Volaric´, Wiktor Szymanski,* Ben L. Feringa* and Giovanni Maglia*
80. Light-controlled inhibition of BRAFV600E kinase
Eur. J. Med. Chem. 2019, 179, 133-146
Mark W. H. Hoorens, Maria E.Ourailidou, Theo Rodat, Petra E. van der Wouden, Piermichele Kobauri, Malte Kriegs, Christian Peifer, Ben L. Feringa, Frank J. Dekker, Wiktor Szymanski*
79. Iminothioindoxyl as a molecular photoswitch with 100 nm band separation in the visible range
Nat. Commun. 2019, 10, 2390
Mark W.H. Hoorens, Miroslav Medved’, Adčle D. Laurent, Mariangela Di Donato, Samuele Fanetti, Laura Slappendel, Michiel Hilbers, Ben L. Feringa,* Wybren Jan Buma,* Wiktor Szymanski*
78. Comparative study of photoswitchable zinc finger domain and AT-hook motif for light-controlled peptide-DNA binding
Chem. Eur. J. 2019, 25, 4965-4973
Gosia M. Murawska, Claudia Poloni, Nadja A. Simeth, Wiktor Szymanski,* and Ben L. Feringa*
77. Following nanomedicine activation with magnetic resonance imaging: why, how, and what’s next?
Curr. Opin. Biotech. 2019, 58, 9-18
Friederike Reeßing, Wiktor Szymanski*
76. Controlling the Circadian Clock with High Temporal Resolution through Photodosimetry
J. Am. Chem. Soc. 2019, 141, 15784-15791
Dušan Kolarski, Akiko Sugiyama, Ghislain Breton, Christin Rakers, Daisuke Ono, Albert Schulte, Florence Tama, Kenichiro Itami, Wiktor Szymanski, Tsuyoshi Hirota* and Ben L. Feringa*
75. Easily Accessible, Highly Potent, Photocontrolled Modulators of Bacterial Communication
Chem. 2019, 5, 1293-1301.
Mickel J. Hansen, Jacques I.C. Hille, Wiktor Szymanski, Arnold J.M. Driessen, Ben L. Feringa*
74. Taming the complexity of donor–acceptor Stenhouse adducts: IR motion pictures of the complete switching pathway
J. Am. Chem. Soc. 2019, 141, 7376-7384
Habiburrahman Zulfikri, Mark A.J. Koenis, Michael M. Lerch, Mariangela Di Donato, Wiktor Szymanski, Claudia Filippi, Ben L. Feringa*, and Wybren Jan Buma*
73. Molecular Motors in Aqueous Environment
J. Org. Chem. 2018, 83, 11008–11018
Anouk S. Lubbe, Christian Böhmer, Filippo Tosi, Wiktor Szymanski,* Ben L. Feringa*
72. Reversible, spatial and temporal control over protein activity using light
Trends Biochem. Sci. 2018, 43, 567-575
Mark W. H. Hoorens, Wiktor Szymanski*
71. Solvent Effects on the Actinic Step of Donor–Acceptor Stenhouse Adduct Photoswitching
Angew. Chem. Int. Ed. 2018, 57, 8063-8068
Michael M. Lerch, Mariangela Di Donato, Adčle D. Laurent, Miroslav Medved, Alessandro Iagatti, Laura Bussotti, Andrea Lapini, Wybren Jan Buma, Paolo Foggi, Wiktor Szymanski,* Ben L. Feringa*
70. Glutamate Transporter Inhibitors with Photo-controlled Activity
Adv. Therap. 2018, 1, 1800028
Mark W. H. Hoorens, Haigen Fu, Ria H. Duurkens, Gianluca Trinco, Valentina Arkhipova, Ben L. Feringa, Gerrit J. Poelarends, Dirk J. Slotboom, Wiktor Szymanski*
69. Photoswitching of DNA hybridization using a molecular motor
J. Am. Chem. Soc. 2018, 140, 5069–5076
Anouk S. Lubbe, Qing Liu, Sanne J. Smith, Jan Willem de Vries, Jos C. M. Kistemaker, Alex H. De Vries, Ignacio Faustino, Zhuojun Meng, Wiktor Szymanski,* Andreas Herrmann,* Ben L. Feringa*
68. The (Photo)chemistry of Stenhouse Photoswitches: Guiding Principles and System Design
Chem. Soc. Rev. 2018, 47, 1910-1937
Michael M. Lerch, Wiktor Szymanski,* Ben. L. Feringa*
67. Green-light-sensitive BODIPY photoprotecting groups for amines
J. Org. Chem. 2018, 83, 1819-1827
Kaja Sitkowska, Ben. L. Feringa, Wiktor Szymanski*
66. Photocontrol of Antibacterial Activity: Shifting from UV to Red Light Activation
J. Am. Chem. Soc 2017, 139, 17979–17986
Michael Wegener, Mickel J. Hansen, Arnold J. M. Driessen, Wiktor Szymanski,* Ben L. Feringa*
65. Two-Step, One-Pot Synthesis of Visible-Light-Responsive 6-Azopurines
Org. Lett. 2017, 19, 5090-5093
Dusan Kolarski, Wiktor Szymanski,* Ben L. Feringa*
64. Recent Developments in Reversible Photoregulation of Oligonucleotide Structure and Function
Chem. Soc. Rev. 2017, 46, 1052-1079
Anouk S. Lubbe, Wiktor Szymanski,* Ben L. Feringa*
63. Beyond Photodynamic Therapy: Light-Activated Cancer Chemotherapy
Curr. Med. Chem. 2017, 24, 4905-4950
Friederike Reeßing and Wiktor Szymanski*
62. Photoactivation of MDM2 Inhibitors: Controlling Protein–Protein Interaction with Light
J. Am. Chem. Soc. 2018, 140, 13136–13141
Mickel J. Hansen, Femke M. Feringa, Piermichele Kobauri, Wiktor Szymanski, René H. Medema*, and Ben L. Feringa*
61. Shedding Light on the Photo-Isomerization Pathway of Donor–Acceptor Stenhouse Adducts
J. Am. Chem. Soc. 2017, 15596–15599
Mariangela Di Donato, Michael M. Lerch, Andrea Lapini, Adčle D. Laurent, Alessandro Iagatti, Laura Bussotti, Svante P. Ihrig, Miroslav Medved, Denis Jacquemin, Wiktor Szymanski, Wybren Jan Buma, Paolo Foggi, and Ben L. Feringa*
60. Tailoring photoisomerization pathways in donor-acceptor Stenhouse adducts: the role of the hydroxyl group
J. Phys. Chem. A 2018, 122, 955–964
Michael M. Lerch, Miroslav Medved, Andrea Lapini, Adčle D. Laurent, Alessandro Iagatti, Laura Bussotti, Wiktor Szymanski, Wybren J. Buma, Paolo Foggi, Mariangela Di Donato,* Ben L. Feringa
59. Elucidation of the biosynthetic pathway for the production of the pigment chrysogine by Penicillium chrysogenum
Appl. Environ. Microbiol. 2018, 84, e02246-17
Annarita Viggiano, Oleksandr Salo, Hazrat Ali, Wiktor Szymanski, Peter P. Lankhorst, Yvonne Nygĺrd, Roel A.L. Bovenberg, Arnold J.M. Driessen*
58. Oxygen activated, palladium nanoparticle catalyzed, ultrafast cross-coupling of organolithium reagents
Angew. Chem. Int. Ed. 2017, 56, 3354–3359
Dorus Heijnen, Filippo Tosi, Carlos Vila, Marc C. A. Stuart, Philip H. Elsinga, Wiktor Szymanski and Ben L. Feringa*
57. HDAC1 and HDAC3 underlie dynamic H3K9 acetylation during embryonic neurogenesis and in schizophrenia-like animals
J. Cell. Physiol, 2018, 233, 530
Josef Vecera, Eva Bartova, Jana Krejci, Sona Legartova, Denisa Komurkova, Jana Kucerova, Tibor Stark, Eva Drazanova, Tomas Kasparek, Alexandra Sulcova, Frank Dekker, Wiktor Szymanski, Christian Seiser, Georg Weitzer, Raphael Mechoulam, Vincenzo Micale, Stanislav Kozubek
56. Rapid Chemoenzymatic Route to Glutamate Transporter Inhibitor L-TFB-TBOA and Related Amino Acids
Org. Biomol. Chem. 2017, 15, 2341-2344
Haigen Fu, Sabry H. H. Younes, Mohammad Saifuddin, Pieter G. Tepper, Jielin Zhang, Erik Keller, André Heeres, Wiktor Szymanski, Gerrit J. Poelarends*