Publications 2021-2022
114. Activiteit van geneesmiddelen reguleren met licht
Ned. Tijdschr. Geneeskd. 2023, 167, D7444
I. M. Welleman, W. Szymanski*
113. Molecular engineering to enhance reactivity and selectivity in an ultrafast photoclick reaction
Angew. Chem. Int. Ed. 2023, ASAP
Y. Fu, N. A. Simeth, R. Toyoda, R. Brilmayer, W. Szymanski,* B. L. Feringa*
112. Patient-derived parathyroid organoids as a tracer and drug-screening application model
Stem Cell Rep. 2022, 17, 2518-2530
M. E. Noltes. L. H.J.Sondorp, L. Kracht, I. F. Antunes, R. Wardenaar, W. Kelder, A. Kemper, W. Szymanski, W. T. Zandee, L. Jansen, A. H. Brouwers, R. P. Coppes, S. Kruijff
111. Design and Synthesis of Visible Light-responsive Azobenzene Building Blocks for Chemical Biology
J. Org. Chem. 2022, 87, 14319–14333
J. Volaric, J. Buter, A. M. Schulte, K.-O. van den Berg, E. Santamaría-Aranda, W. Szymanski,* B. L. Feringa*
110. Photoswitchable, Water-soluble Bis-azobenzene Cross-linkers with Enhanced Properties for Biological Applications
ChemPhotoChem 2022, 6, e202200170
J. Volaric, S. Thallmair, B. L. Feringa,* W. Szymanski*
109. A Strategy for Engineering High Photolysis Efficiency of Photocleavable Protecting Groups Through Cation Stabilization
J. Am. Chem. Soc. 2022, 144, 12421-12430
A. Schulte, G. Alachouzos,* W. Szymanski,* and B.L. Feringa*
108. Light-Control over Casein Kinase 1delta Activity with Photopharmacology: A Clear Case for Arylazopyrazole-Based Inhibitors
Int. J. Mol. Sci. 2022, 23, 5326
A. Schulte, D. Kolarski, V. Sundaram, A. Srivastava, F. Tama, B.L. Feringa,* W. Szymanski*
107. Hypothesis-Driven, Structure-based Design in Photopharmacology: the Case of eDHFR Inhibitors
J. Med. Chem. 2022, 65, 4798–4817
P. Kobauri, N. Galenkamp, A. Schulte, J. de Vries, N. A. Simeth, G. Maglia, S. Thallmair, D. Kolarski, W. Szymanski,* B. L. Feringa*
106. A proof-of-concept study on the use of a fluorescein-based 18F-tracer for pretargeted PET
EJNMMI Radiopharmacy and Chemistry 2022, 7, 3
H. Helbert, E. M. Ploeg, D. F. Samplonius, S. N. Blok, I. F. Antunes, V. I. Böhmer, G. Luurtsema, R. A. J. O. Dierckx, B. L. Feringa, P. H. Elsinga,* W. Szymanski,* W. Helfrich
105. Computational Design, Synthesis, and Photochemistry of Cy7PPG, an Efficient NIR-Activated Photolabile Protecting Group for Therapeutic Applications
Angew. Chem. Int. Ed. 2022, 61, e202201308
G. Alachouzos, A. M. Schulte, A. Mondal, W. Szymanski,* B. L Feringa*
104. Targeted optical fluorescence imaging: a meta-narrative review and future perspectives
EJNMMI 2021, 48, 4272–4292
H. M. Schouw, L. A. Huisman, Y. F. Janssen, R. H. J. A. Slart, R. J. H. Borra, A. T. M. Willemsen, A. H. Brouwers, J. M. van Dijl, R. A. Dierckx, G. M. van Dam, W. Szymanski, H. H. Boersma, S. Kruijff*
103. Phenylimino Indolinone: a Green Light Responsive T-Type Photoswitch Exhibiting Negative Photochromism
Angew. Chem. Int. Ed. 2021, 60, 25290-25295
Stefano Crespi,* Nadja A. Simeth, Mariangela Di Donato, Sandra Doria, Charlotte N. Stindt, Michiel F. Hilbers, Ferdinand L. Kiss, Ryojun Toyoda, Sammo Wesseling, Wybren Jan Buma, Ben L. Feringa,* Wiktor Szymanski*
102. Molecular photoswitches in aqueous environments
Chem. Soc. Rev. 2021, 50, 12377 - 12449
Jana Volaric, Wiktor Szymanski, Nadja A. Simeth,* Ben L. Feringa*
101. Let’s embrace optical imaging: a growing branch on the clinical molecular imaging tree (Editorial)
EJNMMI 2021, 48, 4120–4128
Milou E. Noltes, Gooitzen M. van Dam, Wouter B. Nagengast, Pieter J. van der Zaag, Riemer H. J. A. Slart, Wiktor Szymanski, Schelto Kruijff, Rudi A. J. O. Dierckx*
100. Ultrafast Photoclick Reaction for Selective 18F-Positron Emission Tomography Tracer Synthesis in Flow
J. Am. Chem. Soc. 2021, 143, 10041-10047
Youxin Fu, Hugo Helbert, Nadja A. Simeth, Stefano Crespi, Gerbren B. Spoelstra, Jan Maarten van Dijl, Marleen van Oosten, Luiza Reali Nazario, Dion van der Born, Gert Luurtsema, Wiktor Szymanski,* Philip H. Elsinga,* Ben L. Feringa*
99. Rational Design of a Photoswitchable DNA Glue Enabling High Regulatory Function and Supramolecular Chirality Transfer
Chem. Sci. 2021, 12, 9207-9220
Nadja A. Simeth, Shotaro Kobayashi, Piermichele Kobauri, Stefano Crespi, Wiktor Szymanski, Kazuhiko Nakatani,* Chikara Dohno,* and Ben L. Feringa*
98. Reversible Modulation of Circadian Time with Chronophotopharmacology
Nat. Comm. 2021, 12, 3164
Dušan Kolarski, Carla Miró Vinyals, Akiko Sugiyama, Ashutosh Srivastava, Daisuke Ono, Yoshiko Nagai, Mui Iida, Kenichiro Itami, Florence Tama, Wiktor Szymanski,* Tsuyoshi Hirota,* Ben L. Feringa*
97. Mechanism of Resistance Development in E. coli against TCAT, a Trimethoprim-Based Photoswitchable Antibiotic
Pharmaceuticals 2021, 14, 392
Anna I. Lauxen, Piermichele Kobauri, Michael Wegener, Mickel J. Hansen, Nicole S. Galenkamp, Giovanni Maglia, Wiktor Szymanski,* Ben L. Feringa* and Oscar P. Kuipers*
96. Biaryl sulfonamides as cisoid azosteres for photopharmacology
Chem. Comm. 2021, 57, 4126-4129
Piermichele Kobauri, Wiktor Szymanski,* Fangyuan Cao, Sebastian Thallmair, Siewert J. Marrink, Martin D. Witte, Frank J. Dekker* and Ben L. Feringa*
95. Reductive stability evaluation of 6-azopurine photoswitches for the regulation of CKIa activity and circadian rhythm
Org. Biomol. Chem. 2021, 19, 2312 - 2321
Dušan Kolarski, Akiko Sugiyama, Theo Rodat, Albert Schulte, Christian Peifer, Kenichiro Itami, Tsuyoshi Hirota,* Ben L. Feringa,* and Wiktor Szymanski*
94. Tailoring the optical and dynamic properties of iminothioindoxyl photoswitches through acidochromism
Chem. Sci. 2021, 12, 4588-4598
Miroslav Medved,* Mark W. H. Hoorens, Mariangela Di Donato, Adčle D. Laurent, Jiayun Fan, Maria Taddei, Michiel Hilbers, Ben L. Feringa, Wybren Jan Buma, Wiktor Szymanski*
93. Photopharmacological Manipulation of Mammalian CRY1 for Regulation of the Circadian Clock
J. Am. Chem. Soc. 2021, 143, 2078–2087
Dušan Kolarski, Simon Miller, Tsuyoshi Oshima, Yoshiko Nagai, Yugo Aoki, Piermichele Kobauri, Ashutosh Srivastava, Akiko Sugiyama, Kazuma Amaike, Ayato Sato, Florence Tama, Wiktor Szymanski, Ben L. Feringa,* Kenichiro Itami,* and Tsuyoshi Hirota*
92. Structural Aspects of Photopharmacology: Insight into the Binding of Photoswitchable and Photocaged Inhibitors to the Glutamate Transporter
J. Am. Chem. Soc. 2021, 143, 1513–1520
Valentina Arkhipova, Haigen Fu, Mark W. H. Hoorens, Gianluca Trinco, Lucien N. Lameijer, Egor Marin, Ben L. Feringa, Gerrit J. Poelarends, Wiktor Szymanski,* Dirk J. Slotboom,* and Albert Guskov*
91. Multivalent Probes in Molecular Imaging: Reality or Future?
Trends Mol. Med. 2021, 27, 379-393
Verena I. Boehmer, Wiktor Szymanski, Ben L. Feringa, Philip H. Elsinga*
90. Cross-coupling of [11C]methyllithium for 11C-labeled PET tracer synthesis
Chem. Comm. 2021, 57, 203-206
Hugo Helbert, Inęs Farinha Antunes, Gert Luurtsema, Wiktor Szymanski, Ben L. Feringa,* Philip H. Elsinga*