Publications 2006-2012

24. Engineering methylaspartate ammonia lyase for the asymmetric synthesis of unnatural amino acids

Nature Chem., 2012, 4, 478–484

Hans Raj, Wiktor Szymanski, Jandré de Villiers, Henriëtte J. Rozeboom, Vinod Puthan Veetil, Carlos R. Reis, Marianne de Villiers, Frank J. Dekker, Stefaan de Wildeman, Wim J. Quax, Andy-Mark W. H. Thunnissen, Ben L. Feringa, Dick B. Janssen, Gerrit J. Poelarends*

23. A Simple Enantioconvergent and Chemoenzymatic Synthesis of Optically Active alpha-Substituted Amides

Angew. Chem. Int. Ed., 2011, 50(45), 10712–10715

Wiktor Szymanski, Alja Westerbeek, Dick B. Janssen,* Ben L. Feringa*

22. Mechanism-Inspired Engineering of Phenylalanine Aminomutase for Enhanced beta-Regioselective Asymmetric Amination of Cinnamates

Angew. Chem. Int. Ed., 2012, 51(2), 482–486

Bian Wu, Wiktor Szymanski, Gjalt G. Wybenga, Matthew M. Heberling, Sebastian Bartsch, Stefaan de Wildeman, Gerrit J. Poelarends, Ben L. Feringa, Bauke W. Dijkstra Dick B. Janssen*

21. Recent advances in the catalytic asymmetric synthesis of beta-amino acids

Chem. Soc. Rev., 2010, 39, 1656-16915

Barbara Weiner, Wiktor Szymanski, Dick B. Janssen, Adriaan J. Minnaard, Ben L. Feringa*

20. One pot ‘click’ reactions: tandem enantioselective biocatalytic epoxide ring opening and [3+2] azide alkyne cycloaddition

Chem. Commun., 2010, 46, 898-900

Lachlan S. Campbell-Verduyn, Wiktor Szymanski, Christiaan P. Postema, Rudi A. Dierckx, Philip H. Elsinga,* Dick B. Janssen,* Ben L. Feringa*

19. Engineering of an enantioselective tyrosine aminomutase by mutation of a single active site residue in phenylalanine aminomutase

Chem. Commun., 2010, 46, 8157-8159

Bian Wu, Wiktor Szymanski, Hein J. Wijma, Ciprian G. Crismaru, Stefaan de Wildeman, Gerrit J. Poelarends, Ben L. Feringa, Dick B. Janssen*

18. Combining Designer Cells and Click Chemistry for a One-Pot Four-Step Preparation of Enantiopure beta-Hydroxytriazoles

Adv. Synth. Cat. 2010, 352(13), 2111–2115

Wiktor Szymanski, Christiaan P. Postema, Chiara Tarabiono, Florian Berthiol, Lachlan Campbell-Verduyn, Stefaan de Wildeman, Johannes G. de Vries, Ben L. Feringa and Dick B. Janssen

17. Kinetic Resolution of alpha-Bromoamides: Experimental and Theoretical Investigation of Highly Enantioselective Reactions Catalyzed by Haloalkane Dehalogenases

Adv. Synth. Cat. 2011, 353(6), 931-944

Alja Westerbeek, Wiktor Szymanski, Hein J. Wijma, Siewert J. Marrink, Ben L. Feringa and Dick B. Janssen*

16. Dynamic Kinetic Resolution Process Employing Haloalkane Dehalogenase

ACS Catal., 2011, 1 (12), 1654–1660

Alja Westerbeek, Wiktor Szymanski, Ben L. Feringa, Dick B. Janssen*

15. Enantiomerically pure beta-phenylalanine analogues from alph–beta-phenylalanine mixtures in a single reactive extraction step

Chem. Commun., 2010,46, 901-903

Bastiaan JV Verkuijl, Wiktor Szymanski, Bian Wu, Adriaan J Minnaard,* Dick B Janssen,* Johannes G de Vries,* Ben L Feringa*

14. Aminomutases: mechanistic diversity, biotechnological applications and future perspectives

Trends Biotech. 2011, 29(7) 352–362

Bian Wu, Wiktor Szymanski, Matthew M. Heberling, Ben L. Feringa, Dick B. Janssen*

13. Efficient Tandem Biocatalytic Process for the Kinetic Resolution of Aromatic beta-Amino Acids

Adv. Synth. Catal. 2010, 352(9), 1409–1412

Bian Wu, Wiktor Szymanski, Stefaan de Wildeman, Gerrit J. Poelarends, Ben L. Feringa, Dick B. Janssen*

12. Haloalkane dehalogenase catalysed desymmetrisation and tandem kinetic resolution for the preparation of chiral haloalcohols

Tetrahedron, 68(37), 7645–7650

Alja Westerbeek, Jan G.E. van Leeuwen, Wiktor Szymanski, Ben L. Feringa, Dick B. Janssen*

11. Characterization of a thermostable methylaspartate ammonia lyase from Carboxydothermus hydrogenoformans

Appl. Microb. Biotechnol., 2012, 94(2), 385-397,

Hans Raj, Vinod Puthan Veetil, Wiktor Szymanski, Frank J. Dekker, Wim J. Quax, Ben L. Feringa, Dick B. Janssen, Gerrit J. Poelarends*

10. Phenylalanine Aminomutase-Catalyzed Addition of Ammonia to Substituted Cinnamic Acids: a Route to Enantiopure Amino Acids

J. Org. Chem., 2009, 74 (23), 9152–9157

Wiktor Szymanski, Bian Wu, Barbara Weiner, Stefaan de Wildeman, Ben L. Feringa* and Dick B. Janssen*

9. Enzymatic Synthesis of Enantiopure Amino Acids by Phenylalanine Aminomutase-Catalysed Amination of Cinnamic Acid Derivatives

ChemBioChem, 2009, 10(2), 338–344

Bian Wu, Wiktor Szymanski, Piet Wietzes, Stefaan de Wildeman, Gerrit J. Poelarends, Ben L. Feringa, Dick B. Janssen*

8. Catalytic Enantioselective Synthesis of Vicinal Dialkyl Arrays

J. Org. Chem., 2008, 73 (18), 6994–7002

Anthoni W. van Zijl, Wiktor Szymanski, Ferrnando López, Adriaan J. Minnaard,* Ben L. Feringa*

7. Alpha-Amino acids as acid components in the Passerini reaction: influence of N-protection on the yield and stereoselectivity

Tetrahedron, 2008, 64(41), 9780–9783

Stanislaw Berlozecki, Wiktor Szymanski, Ryszard Ostaszewski*

6. pplication of Isocyanides Derived from Amino Acids as Substrates for the Ugi Reaction

Synth. Commun., 2008, 38(16), 2714-2721

Stanislaw Berlozecki, Wiktor Szymanskia, Ryszard Ostaszewski*

5. Toward stereocontrolled, chemoenzymatic synthesis of unnatural peptides

Tetrahedron, 2008, 64(14), 3197–3203

Wiktor Szymanski, Ryszard Ostaszewski*

4. Solvent-Free Passerini Reactions

Synth. Commun., 2008, 38(7), 2714-2721

Dominik Koszelewski, Wiktor Szymanski, Joanna Krysiak, Ryszard Ostaszewski*

3. Studies on the application of the Passerini reaction and enzymatic procedures to the synthesis of tripeptide mimetics

Tetrahedron, 2007, 63(32), 7647–7653

Wiktor Szymanski, Magdalena Zwolinska, Ryszard Ostaszewski*

2. Chemoenzymatic synthesis of enantiomerically enriched alpha-hydroxyamides

J. Mol. Cat. B Enz. 2007, 47(3-4), 125–128

Wiktor Szymanski, Ryszard Ostaszewski*

1. Multicomponent diversity and enzymatic enantioselectivity as a route towards both enantiomers of alpha-amino acids—a model study

Tetrahedron: Asymmetry, 2006, 17(18), 2667–2671

Wiktor Szymanski, Ryszard Ostaszewski*